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- RESEARCH FIELD(S)1
Dynamic systems, molecular oscillators, ATP and GTP, biophysics, mathematics and computational biology, actin cytoskeleton
- JOB DESCRIPTION
Molecular machines and motors allow cells to perform different functions by using the energy produced by ATP or GTP hydrolysis. While some proteins, such as the myosins in our muscles, convert ATP energy into mechanical work on their own, other motors require the coordinated action of multiple proteins. For these systems, molecular mechanisms at play are misunderstood because they emerge from complex interaction networks yielding collective behaviors.
This project proposes to develop new tools and methods to address this problem by comparing two model systems. The first model is the assembly of the actin cytoskeleton, which requires several proteins and ATP to sustain efficient force generation over long periods of time. The second model is a molecular oscillator, which uses GTP to promote the spatial activation of motility in bacteria.
- QUALIFICATIONS/SKILLS/EDUCATION & RESEARCH REQUIREMENTS
This project is adapted to a student from a physics, mathematics or computational science background, with basic knowledge in biology. The project will eventually require a good level in multiple disciplines, so the recruited student is expected to be curious and motivated in gaining knowledge in the disciplines that would have been less covered in the course of his curriculum.
Host teams are strongly interdisciplinary, so the student will have to interact with many different colleagues and should have the personality to do so.
- APPLICATION DEADLINE
February 16, 2022
- STARTING DATE
October 2022
- JOB LOCATION
Aix Marseille University at the Luminy Campus – Marseille
- REQUESTED DOCUMENTS OF APPLICATION
Application must include:
- CV
- cover letter
An email will be automatically sent to your two references in order for them to upload their recommendation letter directly. We invite you to contact them to make sure that they have received the email.
- CONTACT TO APPLY
