The German Institute of Human Nutrition Potsdam-Rehbruecke (DIfE) is a member of the Leibniz Association. The institute’s mission is to conduct experimental and clinical research in the field of nutrition and health, with the aim of understanding the molecular basis of nutrition-dependent diseases, and of developing new strategies for treatment and prevention (https://www.dife.de/en/).
The Junior Research Group Muscle Physiology and Metabolism (MPM) is inviting applications for one
starting in January 2024.
Obesity and its metabolic complications such as type 2 diabetes plague our healthcare system. While recent advances in pharmacotherapy are promising to treat obesity, cost-effective and widely available solutions are lacking. Interestingly, dietary intake of special lipids called medium-chain fatty acids (MCFAs), which are fatty acids consisting of 8–12 carbon atoms, has been shown to increase energy expenditure, to limit food intake, and to improve insulin resistance. We very recently found that intake of a small amount of MCFAs can help prevent insulin resistance in humans overfed with a high-fat diet. Despite these diverse systemic metabolic benefits, the mechanisms for how MCFAs achieve these effects are completely unknown.
Using cell culture techniques and in vivo experimentation with transgenic mice, it will be your mission to investigate the mode-of-action for how MCFAs benefit health. This work has the potential to uncover new pathways within or among different organs that can be discreetly targeted to elicit distinct, personalized metabolic benefits to treat and/or prevent metabolic diseases.
Your Skills and Requirements:
- Excellent PhD in life sciences, biology, biochemistry, or similar
- Experience in conducting animal studies within the area of nutrition or metabolism
- Experience in working with cell culture
- Laboratory skills related to metabolism, biochemistry, and molecular biology
- Experience with data analyses, interpretation, and presentation
- Curious mindset, intrinsic motivation, and ability to work independently in an interactive research environment
- Excellent English language skills
- Innovative research focused on understanding human metabolic complications
- Working in a vibrating and scientifically stimulating environment
- Excellent facilities and state-of-the-art equipment for metabolic and nutrition research
- Excellent academic networking opportunities (nationally and internationally)
- High degree of autonomy and flexibility
- Support in developing management and grant writing skills
- Support mobility with a jobticket for using the public transport
The advertised position is initially available for a duration of three years. The level of salary will be determined on the basis of standard / tariff conditions, present qualifications, and professional experience (TV-L, level E 13).
We are looking forward to your application!
Kindly submit your documents (cover letter detailing your motivation, CV, work and degree certificates, and references) with reference number 2023_W06_AP in one PDF file by e-mail to firstname.lastname@example.org.
For further information please do not hesitate to contact:
Dr. Maximilian Kleinert
Head of the Junior Research Group
Muscle Physiology and Metabolism
By submitting your application documents, you grant us the right to collect, process, and use your personal data exclusively for the application selection process. For further information about your rights according to the data protection law, please contact the department Human Resources and Social Services (email@example.com).