Postdoctoral Fellows in Immunology / Bioinformatics, Boston University

USA
Posted 3 months ago

The Boston University Pulmonary Center, Bosmann Laboratory is recruiting 2 Postdoctoral Fellows for projects on Innate Immunity of Infections.

Acute respiratory distress syndrome (ARDS), pneumonia and sepsis are life-threatening complications of microbial infections with profound disturbances of the immune system. In the current absence of definitive treatment options, ARDS and sepsis represent an enormous problem for health systems worldwide. Our laboratory is dedicated to obtain a better mechanistic understanding of the molecular pathogenesis of bacterial, viral and parasitic infections for the evaluation of new therapeutic targets. Please see our recent publications in Nature Communications. 2020 Aug 12;11(1):4035 and Mucosal Immunology. 2022 Jun 7;1-13.

Immunology: We are looking for a highly motivated Postdoctoral Fellow in Immunology for experimental research. Special areas of interest are the role and structure of novel genes involved in inflammation, pathogen recognition, host-pathogen interactions, macrophages, neutrophils, cytokines, and related signaling pathways. Pathogens of interest are Legionella spp.S. pneumoniaeE. coliN. brasiliensisSARS-CoV-2Influenza and others. Several kockout mouse strains generated by our laboratory are available. The projects will be tailored to meet the individual qualifications and interests of the trainee.

Bioinformatics: We are looking for a highly motivated Postdoctoral Fellow in Bioinformatics for data science. The projects will use novel data sets generated in our laboratory (bulk RNAseq, scRNAseq, CITEseq/TOTALseq, scATACseq, spatial transcriptomics, and phospho-/proteomics) as well as open access resources. Knowledge of a general-purpose programming language such as R is desirable. The training opportunities in analysis using R-based packages (e.g., DESeq2, Seurat) will be supported by an experienced Bioinformatician in our laboratory and through collaboration with the Division of Computational Biomedicine of our Department.

We are especially interested in candidates with prior experiences in immunology or bioinformatics and with excellent scientific writing skills.

Further information is available:

http://www.bumc.bu.edu/pulmonary/people/markus-bosmann-m-d/

https://www.unimedizin-mainz.de/cth/professorships-work-groups/dr-bosmann.html?L=1

Please send your CV, publication list, transcripts and names of three references to:

Markus Bosmann (mbosmann@bu.edu), M.D., Associate Professor of Medicine, Pathology & Laboratory Medicine, Investigator of the National Emerging Infectious Diseases Laboratories

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