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ENLIGHT-TEN+ Early Stage Researcher PhD Three-Year PhD Studentship at the Wellcome Sanger Institute
Registered at the University of Cambridge
European Network Linking Informatics and Genomics of Helper T cells in Tissues: Dissection of CD4+ T cell states across human tissues
ENLIGHT-TEN+, a Marie Sklodowska-Curie Innovative Training Network (ITN-ETN) funded in the framework of the HORIZON 2020 program, is aiming to link informatics and genomics of helper T cells in tissues. A crucial missing link in our current research environment is the lack of qualified individuals who possess the cellular immunology skills to recognise and define important scientific questions amenable to -omics approaches and also the bioinformatic expertise to interrogate and interpret the resulting big data appropriately. Thus, our mission is to provide cross-disciplinary training for a new generation of enthusiastic researchers who have in-depth understanding of T cell immunology and are also capable to handle large datasets. The network of 15 beneficiaries from 10 European countries combines ample expertise on T cell biology with state-of-the-art technologies generating big data, cutting-edge bioinformatic tools including artificial intelligence, preclinical models and samples from patient cohorts. ENLIGHT-TEN+ will identify microenvironmental factors shaping the functional properties of tissue-resident T cells, which offer important therapeutic potential in various human autoimmune diseases, making them a key target for pharmaceutical companies. The Early Stage Researcher (ESR) will be empowered to push our knowledge of tissue-resident T cells beyond the state-of-the-art which will enable the identification of novel biomarkers and support the development of advanced therapeutic concepts. ENLIGHT-TEN+ will combine individual strengths of innovative laboratories and enterprises from complementary disciplines to provide unique interdisciplinary training as an ideal stepping-stone for the ESR to enter and strengthen Europe’s academia as well as pharmaceutical and bioinformatics companies, thereby placing them at the forefront of this emerging field. More information on the ENLIGHT-TEN+ consortium can be found here: www.enlight-ten.eu.
The ESR will be positioned at the Wellcome Sanger Institute, a world leading genomics institute, under the supervision of Sarah Teichmann. Please visit Sarah’s faculty page for more information about her research areas: https://www.sanger.ac.uk/person/teichmann-sarah/.
Fellowship: The monthly gross salary will be in accordance with the EC Marie Skłodowska-Curie rates and will be paid by the host organisation. The salary may be subjected to tax according to applicable national regulations. The position is aimed at being full-time and is designed for a duration of 36 months.
The mobility allowance is due if the researcher is relocating to the UK.
The family allowance is due if the researcher has a family at the time of recruitment. ‘Family’ means persons linked to the researcher by marriage (or a relationship with equivalent status to a marriage recognised by the legislation of the country where this relationship was formalised) or dependent children who are actually being maintained by the researcher.
Additional Information: This project has received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement Number: 955321.
In accordance with the European Charter and Code of Conduct, ENLIGHT-TEN+ is committed to an open, transparent, impartial, equitable and merit-based recruitment procedure. By submitting their application, ENLIGHT-TEN+ candidates agree to the storage of their personal data by the Helmholtz Centre for Infection Research. In addition, copies of all evaluations made by project supervisors at every stage of the recruitment process will be retained. Upon demand, data will be communicated to EU officials. Personal data and related documents of all applicants will be kept by the ENLIGHT-TEN+ Consortium until completion of the Project.
Essential Skills
Eligibility criteria:
- You must hold a master degree in a relevant discipline (Biology, Medical/Molecular Biology, Biochemistry, Systems Biology, Bioinformatics, Mathematics, Physics or another relevant discipline), or will receive this before the appointment date.
- You have received your master degree < 4 years before the date of appointment and have not been awarded a PhD degree.
- You can be of any nationality, but have not resided or carried out your main activity (work, studies, etc.) in the UK for more than 12 months during the 3 years immediately prior to the appointment date.
- You must not have spent more than 12 months in the 3 years immediately prior to the date of selection at the Wellcome Sanger Institute.
- You must be available to start your project on 1st March 2022.
