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The Michael Smith Laboratories at the University of British Columbia in Vancouver, Canada, invites applications for a Postdoctoral Fellow (PDF) to join a dynamic and multidisciplinary team under the supervision of Dr. Anna Blakney. The successful candidate will work on a project to develop self-amplifying RNA therapies encoding monoclonal antibodies. The Blakney Lab at UBC (blakneylab.msl.ubc.ca) develops next-generation RNA vaccines and therapies based on self-amplifying RNA and using interdisciplinary approaches including bioengineering, immunology, molecular biology and bioinformatics.
Project: Monoclonal antibodies are highly potent and specific biologic drugs that have revolutionized treatment of cancer and rare diseases. However, they generally require intravenous administration and are costly, which prohibits widespread global use for applications such as prevention of infectious disease. Our goal is to develop self-amplifying RNA formulations that are able to achieve systemic, therapeutically relevant levels of monoclonal antibodies that are able to be injected intramuscularly. We anticipate that this technology will expand global access to antibody therapies that are more equitable.
Candidate: We are hiring post-doctoral bioengineers with a background in antibody design, molecular biology, RNA gene therapies and/or biomaterials. Candidates must have a Ph.D. in biomedical engineering, chemical engineering, molecular biology, chemistry, or similar fields. The candidate must be able to work well on a team, even in situations where an opportunity is more exciting and time-sensitive than normal. We are seeking a creative individual with great interpersonal skills and excellent communication, both written and verbal.
Opportunity: This is a unique opportunity for several reasons. First, you will be a member of a fun, diverse and interdisciplinary group. Second, you will learn about RNA gene therapies. Third, you will be actively involved in projects that are intended for clinical translation. Finally, the University of British Columbia is located in Vancouver, which is world-renowned for its scenery and quality of living. UBC is a center of excellence for growing your career in nanomedicine and gene delivery technologies, and you will have opportunities to collaborate with world-class leaders in the field, such as the Cullis Laboratory, through the Nanomedicine Innovation Network.
Application Process: Interested applicants should submit a CV and cover letter that details their experience and contact details for 3 references. Applications should be submitted to anna.blakney@msl.ubc.ca with ‘PDF saRNA mAbs’ in the email subject line. Applicants for the position will be evaluated in the order they are received.
This posting will remain open until the position is filled. The proposed start date for this position is March 2022 and is negotiable. The appointment will initially be for one year and is extendable depending on funding availability. Applicants are encouraged to apply for competitive fellowship awards. Salary will be commensurate with qualifications, experience and awards secured.
This posting is for the UBC Vancouver campus in British Columbia, Canada.
Please refer to reference number NC-55670 during correspondence about this position. Please visit the researcher profile of the supervisor for this position to learn more about their research.
Equity and diversity are essential to academic excellence. An open and diverse community fosters the inclusion of voices that have been underrepresented or discouraged. We encourage applications from members of groups that have been marginalized on any grounds enumerated under the B.C. Human Rights Code, including sex, sexual orientation, gender identity or expression, racialization, disability, political belief, religion, marital or family status, age, and/or status as a First Nation, Metis, Inuit, or Indigenous person.
About UBC
The University of British Columbia is a global centre for research and teaching, consistently ranked among the top 20 public universities in the world. Since 1915, UBC’s entrepreneurial spirit has embraced innovation and challenged the status quo. UBC encourages its students, staff and faculty to challenge convention, lead discovery and explore new ways of learning. At UBC, bold thinking is given a place to develop into ideas that can change the world.
Postdoctoral Fellows at UBC Vancouver
UBC is home to over 900 postdocs spanning all faculties and units across two campuses and a variety of affiliated hospitals, research centres, and sites, providing unparalleled opportunities to learn, discover and contribute in one’s own way. UBC’s Postdoctoral Fellows Office (PDFO) is committed to supporting the lives and career aspirations of our Postdocs, with the goal of enriching their experience at UBC and preparing them for the future. In addition to providing support and advocacy for all postdocs, the PDFO is dedicated to providing professional development opportunities that foster the development of soft skills needed in today’s professional environments, helping them secure future careers in their chosen fields.
About Vancouver
Vancouver is a dynamic, cosmopolitan and progressive city, consistently ranked as one of the top cities to live in the world. Canada’s third largest city has it all: sea, parks, mountains, beaches, and four seasons per year, including beautiful summers and mild, wet winters with snow in the mountains. It’s the perfect backdrop to your academic research.
