Postdoctoral Fellow Wellcome Trust Sanger Institute

Opportunity:

An opportunity is available for an enthusiastic Postdoctoral Fellow to join the Lee team on a multi-lab collaborative project as part of the Malaria Drug Accelerator (MalDA), funded by the Bill and Melinda Gates Foundation.

About Us:

The goal is to systematically investigate and validate new antimalarial targets in Plasmodium falciparum. The project will use a variety of genetic approaches, including CRISPR/Cas9 genome engineering and multiplex phenotyping assays, and capitalises on existing expertise in the Lee lab developing state-of-the-art CRISPR-based approaches for genome manipulation and drug target validation.

About You:

You will have demonstrated expertise in parasite culture and genetic manipulation, as well as a strong molecular biology background, and will enjoy working in a collaborative research environment. Candidates with experience in high-throughput assay development and liquid handling automation are encouraged to apply. For more information on MalDA, please see (Yang et al., 2021, Trends Parasit., PMID: 33648890).

Essential Skills

Technical:

  • A PhD in microbiology, parasitology, genetics, genomics, or an equivalent area
  • Research experience in malaria biology or a related relevant area
  • Experience and excellent practical skills in eukaryotic cell culture techniques
  • Experience in molecular biology
  • Experience and understanding of biological safety regulations and procedures

Competencies and Behaviours:

  • Motivation and ambition to make a personal contribution to GRL research
  • Excellent communication skills to allow efficient interactions with collaborators
  • Team player with the ability to work with others in a collegiate and collaborative environment
  • Ability to effectively prioritise, multi-task and work independently
  • Demonstrates inclusivity and respect for all
  • Ability to utilise common tool sets such as spreadsheet, flowcharting and presentation packages

Ideal Skills

Technical:

  • Experience with growing and transfecting Plasmodium falciparum parasites
  • Experience in CRISPR/Cas9 methods
  • Experience with project management
  • Experience and understanding of biological safety regulations and procedures, particularly in handling human pathogens

Other information

#HP

Whilst the developments around COVID-19 continue to evolve, the Wellcome Genome Campus is closed for all but essential functions and facilities.

People remain at the centre of everything that we do and the majority of our staff are now working remotely to ensure continuity of operations, making use of remote communication and collaboration tools.

Interviews will be taking place virtually and the successful candidate should expect to be fully supported through remote on-boarding and working from home until the Campus re-opens to all staff. This approach may vary for individuals located overseas and/or where a visa is required and starting will be based on a number of factors, we will be able to provide specialist advice to those affected candidates.

You can find out more about being a Postdoctoral Fellow with us here.

Application Process:

Please apply with your CV for this role by closing date 30th May 2021.

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