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A postdoctoral position in the laboratory of Dr. Walker is available to work in translational research studies in multiple myeloma. Highly motivated individuals with a PhD in the area of cell and molecular biology, genomics, epigenetics, cancer biology or related fields are encouraged to apply. This position is to perform comprehensive genomics on patient samples, cell lines, and patient derived xenografts to identify mechanisms leading to high-risk disease. The successful candidate will use genomic, epigenetic, and cellular studies to determine how genome organization leads to dysregulated epigenetic and expression signatures leading to high-risk disease, progression and relapse.
Duties or techniques may include, but are not limited to, the following:
- Cell sorting by flow cytometry or magnetic beads
- Cell culture
- Lentiviral transduction
- Generation of vectors and reagents
- Western blotting, cellular and protein analysis.
- ChIP-seq
- Hi-C
- CRISPR/Cas9 mutagenesis Animal models
- Drug sensitivity assays
- Maintaining accurate records of experiments and results
- Communicating with other team members and senior departmental members Presenting data locally and at national and international meetings
Relevant publications: https://pubmed.ncbi.nlm.nih.gov/34933939/ https://pubmed.ncbi.nlm.nih.gov/34365473/ https://pubmed.ncbi.nlm.nih.gov/32060406/ https://pubmed.ncbi.nlm.nih.gov/32762714/
As the nation’s largest medical school, IUSM is committed to being an institution that not only reflects the diversity of the learners we teach and the patient populations we serve, but also pursues the values of diversity, equity and inclusion that inform academic excellence. We desire candidates who enhance our representational diversity, as well as those whose work contributes to equitable and inclusive learning and working environments for our students, staff, and faculty. IUSM strives to take an anti-racist stance, regularly evaluating and updating its policies, procedures, and practices to confer equitable opportunities for contribution and advancement for all members of our community. We invite individuals who will join us in our mission to advance racial equity to transform health and wellbeing for all throughout the state of Indiana.
Indianapolis is the capital and most populous city in the State of Indiana. It is growing economically thanks to a strong corporate base anchored by the life sciences. Indiana is home to one of the largest concentrations of health sciences companies in the nation.
Indianapolis has a sophisticated blend of charm and culture with a wonderful balance of business and leisure. The growing residential base is supported by rich amenities and quality of life – the city possesses a variety of professional sports, arts venues and outdoor recreation areas. Residents of this dynamic city, and surrounding suburbs, enjoy leading educational systems and top-ranked universities, paired with a diverse population. Indianapolis International Airport is a top-ranked international airport, being named “Best Airport in North America” by Airports Council International for many years. For additional information on life in Indy: https://faculty.medicine.iu.edu/relocation
The search committee will begin evaluating applications as they are received and applications will continue to be reviewed until positions are filled.
Basic Qualifications
Doctorate or terminal degree required. The candidate should be highly motivated with a PhD in the area of cell and molecular biology, genomics, epigenetics, cancer biology or a related field. The candidate must be diligent, rigorous, able to work independently, approachable and have an attention to detail.
Department Contact for Questions
Sabrina Hetzel
