In a long-standing collaboration between the Gouverneur Group in Oxford chemistry and the Vallis group in Oxford oncology together with the Davis group in the Next Generation Chemistry theme at the Rosalind Franklin Institute, one of the aims is to develop new synthetic chemical methods to edit complex biomolecules as a form of post-translational mutagenesis that allow the development and application of “zero size labelling”.
We are currently seeking a highly-motivated Postdoctoral Research Associate to join our project which will develop new methods for the manipulation of complex protein constructs [see e.g. Nature, 2020, 585, 530]. Within this theme, you will expand on these discoveries and develop new methods for chemical manipulation of proteins to probe fundamental biology and medicine. The post, which is for 3 years, reports to the Franklin’s Theme Lead for Chemistry (Ben Davis), as well as Professor Gouverneur and Professor Vallis as key academic collaborators and will work alongside other researchers in the Franklin and at partner university institutes including at the University of Oxford (where some groups are jointly based).
About you
Candidates must hold a post-graduate qualification/PhD (or equivalent experience) in Chemistry, Biochemistry or Chemical Biology, Biology, Biomolecular Science, or related subjects. We are looking for candidates with a demonstrated aptitude for protein chemistry and associated methods, as well as the ability to discuss and coordinate experiments with a variety of colleagues from different disciplines. Experience in synthetic methods applied to biomolecules and functional application, experience with developing routinely usable methods, and experience with project management are essential for this role.
About us
The Rosalind Franklin Institute is a new national Research Centre, funded by the UK government through UK Research and Innovation, dedicated to bringing about transformative changes in life science through interdisciplinary research and technology.
Location: The Franklin is based in Harwell Campus, UK’s innovation hub and well-established as one of the leading science and innovation campuses in Europe.
Before submitting your application please ensure you read the Job Information Pack for full details of this role by clicking on the attachment on our website: https://opportunities.rfi.ac.uk/vacancy/pdra-in-fluoroprotein-chemical-biology—470726.html
Closing date: 2nd February 2022 at 09:00am
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Area Scientific
Location Harwell and Oxford
Type of Post Full Time
Salary £33,000 – £39,000
Closing Date 02/02/2022
Ref No 10183