PhD position: Discovery, characterization and exploitation of natural product and xenobiotic glycosyltransferases

PhD position

Discovery, characterization and exploitation of

natural product and xenobiotic glycosyltransferases

in Graz / Austria

The Nidetzky group @acib

We are specialists in carbohydrate-active enzymes and their application in biocatalytic syntheses. Our team of around 30 people is located at Graz Technical University. Within ACIB we push enzymes towards industrial application together with our industrial partners.

The project

The advertised project focuses on the discovery and characterization of an insufficiently characterized class of glycosyltransferases, involved in the (bio)synthesis of various bioactive natural product glycosides. The successful applicant will use bioinformatic tools identifying potential new enzyme candidates and will recombinantly express them in an appropriate expression host. High throughput and state of the art methods will be used for a comprehensive enzyme characterization. The overall goal of the project is to deepen the understanding of the biological significance and to gain mechanistic insights into this enzyme class.

That’s your profile

  • You have a strong background and a University degree in biotechnology or related disciplines.
  • You have practical experience with enzymes, including expression, purification and enzymatic assays. Experience in kinetic studies, HPLC analysis, strain engineering, is a plus
  • We are an international group. Excellent skills in spoken and written English are a must.
  • You are highly motivated and good in self organization with strong attention to details
  • You show ambition in research and are committed to excellence

That’s what we offer

You will conduct research in an internationally competitive lab at the interface of biochemistry and chemical biology, learning various new techniques used in contemporary enzymology. You find a cheerful team of motivated colleagues helping each other to max out your potential as aspiring scientist. Additionally, you profit from being involved in the ACIB network of over 200 scientist and industry partners. Time-variable outgoings will be supported gaining experience with our international academic partners.

  • minimum yearly gross payment of EUR 30,870 (PhD 30 h/week)
  • Start: earliest September 2020
  • Get more information on the position by emailing Dr. Gregor Tegl / gtegl@tugraz.at

Find out more about why acib is the right choice for you: www.acib.at/career

And now it’s your turn! Give us an idea of who you are.

Apply here: https://mycareer.acib.at I Ref.no: 12_2020

Application deadline: 31th of August 2020

We welcome applicants of all sexes, backgrounds and ages.

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