Two 3-year-PhD Positions in Isotropic-resolution tomographic diffractive microscopy: 4Pi TDM and mirror-assisted TDM

RESEARCHER PROFILE: PhD / R1: First stage Researcher
RESEARCH FIELD(S) AND DISCIPLINES1: Physics / Optics

JOB /OFFER DESCRIPTION: Tomographic Diffractive Microscopy (TDM) represents state-of-the art in unlabeled optical microscopy, in terms of resolution, and for quantitative measure of sample’s optical properties. This technique is even now commercially available, but in simplified versions. Institut Fresnel and IRIMAS collaborate via an ANR grant, in view of further improving the technique. In particular, the importance of working with isotropic-resolution images is vastly overlooked [1]. Even simple quantities such as volumes cannot be accurately measured at micrometric scale in transmission-only microscopy, because of the so-called “missing-cone” problem [2]. Consequently, index of refraction, or species concentrations are even more difficult to measure with precision [3-5].

We propose 2 PhD theses within the framework of the joint IRIMAS-Fresnel ANR TARANIS grant (1 at IRIMAS and 1 at Fresnel) to study isotropic-resolution TDM. Several approaches are possible: combining sample and illumination rotations as in [1], using a 4Pi setup, as proposed in [2], or using mirror-assisted TDM approach, as demonstrated in [4,5]. The selected candidates will join recognized and active groups in the domain, and will:

Study the underlying principles of TDM (bibliography), become familiar with the operation of the present IRIMAS and Fresnel systems, as well as with the various data reconstruction methods already implemented in the laboratories.

Participate to the construction of 4Pi / mirror-assisted TDM setups

Write advanced reconstruction codes, adapted to these peculiar configurations

Regular scientific visits are planned for PhD students in both Fresnel and IRIMAS institutes.

Simon, B., et al., Tomographic diffractive microscopy with isotropic resolution, Optica 4, 460 (2017)

Lauer, V., New approach to optical diffraction tomography yielding a vector equation of diffraction tomography and a novel tomographic microscope, Journal of Microscopy 205, 165 (2002)

Zhang, T., et al., Far-field diffraction microscopy at λ/10 resolution, Optica 3, 609(2016)

Mudry, E., et al., Mirror-assisted tomographic diffractive microscopy with isotropic resolution, Optics Letters 35, 1857 (2010)

Foucault, L., et al., Versatile transmission reflection tomographic diffractive microscopy approach, Journal of the Optical Society of America A 36, C18 (2019)

• Contact Fresnel: Guillaume Maire guillaume.maire@fresnel.fr, Institut Fresnel, Avenue Escadrille Normandie Niemen, 13397 Marseille Cedex 20, Tel: +33 (0)4 13 94 55 13
• Contact IRIMAS: Olivier Haeberlé/Nicolas Verrier olivier.haeberle@uha.fr nicolas.verrier@uha.fr, IRIMAS – Université de Haute-Alsace 61 rue Albert Camus, 68093 Mulhouse Cedex, Tel: +33 (0)3 89 33 76 11 / 76 66

WHAT WE OFFER 
1720 € net salary per month

The Euraxess Center of Aix-Marseille Université informs foreign visiting professors, researchers, postdoc and PhD candidates about the administrative steps to be undertaken prior to arrival at AMU and the various practical formalities to be completed once in France: visas and entry requirements, insurance, help finding accommodation, support in opening a bank account, etc. More information on AMU EURAXESS Portal

TYPE OF CONTRACT: TEMPORARY/ JOB STATUS: FULL TIME/ HOURS PER WEEK: 35
JOB NOT FUNDED THROUGH AN EU RESEARCH FRAMEWORK PROGRAMME
APPLICATION DEADLINE: 15/09/2023
ENVISAGED STARTING DATE: 01/10/2023
ENVISAGED DURATION: 36 months
WORK LOCATION(S): 

• Institut Fresnel, Campus Universitaire de Saint-Jérôme, 52 Av. Escadrille Normandie Niemen, 13013 Marseille, France for the 1st PhD grant
• IRIMAS, Mulhouse, France for the second PhD grant

QUALIFICATIONS, REQUIRED EDUCATION LEVEL, PROFESSIONAL SKILLS, RESEARCH REQUIREMENTS 
Master degree in Physics, strong analytical skills (Physics, Optics), experimental optics and computational skills (Matlab, C/C++ and/or Python)

SOFT SKILLS: Autonomy, resourcefulness and creativity
REQUESTED DOCUMENTS OF APPLICATION, SELECTION PROCESS
CV, official transcripts of Master degree

WHERE TO APPLY

• Contact Fresnel: Guillaume Maire guillaume.maire@fresnel.fr, Institut Fresnel, Avenue Escadrille Normandie Niemen, 13397 Marseille Cedex 20, Tel: +33 (0)4 13 94 55 13
• Contact IRIMAS: Olivier Haeberlé/Nicolas Verrier olivier.haeberle@uha.fr nicolas.verrier@uha.fr, IRIMAS – Université de Haute-Alsace 61 rue Albert Camus, 68093 Mulhouse Cedex, Tel: +33 (0)3 89 33 76 11 / 76 66