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The team Pharmacology and Technologies for Cardiovascular Diseases at INSERM U955 is looking for a highly skilled and enthusiastic post-doctoral fellow working in a dynamic, international and interactive environment. The position is available from September 2022 and will be funded for 3 years thanks to a Team project grant by the Fondation Recherche Medicale (FRM).
The laboratory is focussing on the study of different therapeutic strategies in the context of cardiovascular disease. In particular, the ‘Heme and myocardial infarction (MI)’ project aims at investigating the role of heme as a dangerous signal during MI. We will closely assess the participation of heme in the activation of the stress response and the reparative process occurring after MI, including the modulation of the inflammatory response. Heme oxygenase-1 (HO-1), the enzyme responsible of heme degradation, and chemical entities targeting the HO-1 pathway will also be evaluated as potential therapeutics. Animal models (murine and pig), as well as human samples from MI patients, will be used in the study.
Highly motivated and dynamic candidates will have a PhD with strong background in rodent models of MI, inflammation and will have knowledge of a variety of approaches spanning from molecular biology, analyses of tissue samples to in vivo experimentation. Candidates should have proven experience on a wide range of methodological techniques (including cell culture, western blotting, RT-PCR, ELISA, isolation of cells from tissues).
Individuals who are interested in the post should email a Curriculum Vitae indicating the project acronym (Heme-MI) with a letter of motivation, research interests, technical skills and the name and email of three referees to: Prof Roberta Foresti (roberta.foresti@inserm.fr) and Prof Bijan Ghaleh (bijan.ghaleh@inserm.fr).
Closing date for applicants: 30 May 2022
Job Features
| Job Category | Teaching and scientific research, Postdoctoral |
