Position as Postdoctoral Researcher in Bioinformatics

Ming Wai Lau Centre for Reparative Medicine (MWLC) aims to contribute to the improvement of human health by conducting cutting-edge research in reparative medicine and related subjects, by creating a new platform for synergies between academia and innovation in Sweden and Hong Kong as well as China, and fostering future leaders in both academia and industry.

MWLC was established to further accelerate research in stem cell biology, biomedical engineering, biotechnology, and regenerative medicine. MWLC operates two nodes, one based at Karolinska Institutet in Stockholm, Sweden and the other in Hong Kong, located in Science Park, Shatin. The Hong Kong node currently includes four research groups, consisting of a total of 40-50 scientists.

Description of the research group and project
Dr. Zongli Zheng’s group has long interests in understanding cell biology related to the CRISPR gene editing system and cancers, as well as in technology innovation to solve clinical problems. Some of our technologies have been adopted globally in both research and clinical settings for precision medicine and for CRISPR genome editing. We are integrating single-cell genomics and CRISPR genome editing to identify molecular determinants, therapeutic targets, biomarkers and solutions for genetic diseases. Companion new data algorithm and software development are integral parts of these developments. We are seeking a highly motivated young scientist to join our team.

Responsibility
The position will be based in the inspiring environment in Hong Kong Science Park. The successful candidate will be working with cell biologists, genetics and computational biology scientists in understanding CRISPR biology and to develop new technology, including precision and efficient genome editing, and to contribute to providing clinical solutions to various genetic diseases. Specific responsibilities include:

• • Design and lead research projects in big data mining in e.g. metagenomics and evolution genomics
  • Develop new data algorithm, statistical models and/or bioinformatics pipelines, with inputs from cell and molecular biologists and computational biologists
  • Data summary and manuscript writing for reporting and scientific journal publications

Qualifications
We are looking the following qualifications, experience and skills:

• • A PhD degree in Metagenomics, Systems Biology, Computational Biology, Bioinformatics or a related discipline
  • Knowledge in statistical methods in the context of biological systems
  • Experience with programming (Python, Perl, or C++) and R
  • Experience with next generation sequencing data processing and analysis
  • Knowledge in CRISPR genome editing is a plus
  • Proficiency in written and spoken English
  • Interested in working at the boundaries of several research domains and able to work in a collaborative team

The employment
This is a one-year fixed-term position, with the possibility of renewal.

The assignment is located at MWLC, Hong Kong, and the employment will follow local labour laws in Hong Kong.

A competitive remuneration package including 10% on top of basic salary (fully-taxable) intended as pension will be offered in addition to MPF employer’s contribution and medical benefits.

Entry requirements
At KI the Postdoctoral researcher position is regarded as an early career step after a doctoral degree. Qualified to be employed as a Postdoctoral researcher is one who has obtained a doctorate or has equivalent scientific competence.

To be qualified for this position, a PhD degree in Metagenomics, Systems Biology, Computational Biology, Bioinformatics or a related discipline is required.

Application process
An employment application must contain the following documents in English:

• A complete curriculum vitae, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
• A degree certificate
• A complete list of publications
• A summary of current work (no more than two page)
• Applicants should arrange to have at least two letters of reference

The application is to be submitted through the Varbi recruitment system.

Interviews will start when applications are received until the position is filled.

First day of employment: ASAP.

Karolinska Institutet is one of the world´s leading medical universities. Its mission is to contribute to the improvement of human health through research and education. Karolinska Institutet accounts for over 40 per cent of the medical academic research conducted in Sweden and offers the country´s broadest range of education in medicine and health sciences. Since 1901 the Nobel Assembly at Karolinska Institutet has selected the Nobel laureates in Physiology or Medicine.

Pursuant to the regulations of the Swedish National Archives, applications are kept on file for two years after the appointment has gained legal force. The regulations do not apply to attachments that have been printed or otherwise published.

Karolinska Institutet strives to provide a workplace that has approximately the same number of women and men, is free of discrimination and offers equal opportunity to everyone.

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