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We are hiring a Postdoctoral Associate in the Lester and Sue Smith Breast Center at Baylor College of Medicine. The Breast Center is a collaborative environment dedicated to breast health and disease research, as well as prevention, diagnosis, and treatment of different forms of breast cancer. We are looking for a candidate with a background in computational biology/bioinformatics who thrives in collaborative research. For more information, visit https://www.bcm.edu/people-search/qian-zhu-119781
Job Duties
- Works in a Cancer Prevention & Research Institute of Texas (CPRIT) funded laboratory focused on computational cancer biology.
- Integrates various modalities of single-cell sequencing data and spatial genomics data to better understand the contribution of spatial multi-cellular environments to cancer formation, progression, and treatment.
- Contributes to the development of new methods or in the advancement of biological knowledge.
- Focuses on one of following:
- Methodological development: The candidate will develop innovative methods to integrate multiple modalities of single cell data to disentangle cell-to-cell variability, and identify novel cell subpopulations that contribute to treatment resistance and cancer recurrence. Methods range from statistical, computational, to machine-learning based. These new methods are expected to benefit the community at large by being broadly applicable to different datasets.
- Applied computational biology: The candidate will use a range of bioinformatics tools to analyze research data in order to glean interesting mechanistic insights during development and cancer progression, and treatment resistance. The candidate is expected to have excellent collaborative skills as he/she is expected to work alongside biologists and clinicians from other laboratories to make impactful discoveries.
Minimum Qualifications
- MD or Ph.D. in Basic Science, Health Science, or a related field.
- No experience required.
Preferred Qualifications
- Needs to have published a first-authored paper in a peer-reviewed journal.
- For candidate in the applied computational biology:
- Knows how to use InferCNV to disentangle copy number variations in cancer genomics data.
- Knows how to use Seurat, Monocle, SCENIC, Dynamo, Velocyto to infer both discrete cell populations and continuous developmental trajectories from single cell RNAseq data.
- Knows how to infer cell-cell communication pairs.
- Knowledge about how to use UK Biobank and All of Us Research data is a plus.
- Knowledge about genetic analysis, such as variant calling, is a plus.
- For candidates in the methods development area:
- Knowledge of probabilities and statistics, probabilistic modeling, Bayesian network, and deep programming knowledge of Python, R, is required.
- Deep learning related experience is a plus.
- The candidate needs to demonstrate ability to implement new algorithms in Python, R, and modify existing implementations written in one of the these languages.
Job Features
| Job Category | Postdoctoral, Sciences Biologiques |
We are hiring a Postdoctoral Associate in the Lester and Sue Smith Breast Center at Baylor College of Medicine. The Breast Center is a collaborative environment dedicated to breast health and disease ...View more
We seek two postdoctoral fellows to join the Mustelin/Najjar lab in the Rheumatology division, University of Washington, Seattle, USA, to lead and collaborate on genomics research projects in systemic autoimmune diseases. These are full-time positions on an annual service period of 12 months (July 1 – June 30). The anticipated start date for these positions is July, 1st 2024.
The fields of autoimmunity and rheumatology have seen important advances in therapeutics that have improved patients’ lives. At the same time, all these advances are based on inhibiting inflammatory molecules that are physiologically important for a healthy immune system. We are interested in the next generation of therapeutics that will be personalized and only target the original disease process. Such treatments can only be created if we reveal the true causes of systemic autoimmune diseases.
Join our lab to help generate and test novel hypotheses in rheumatologic autoimmune diseases. We are looking for highly motivated postdoctoral fellows with expertise in computational biology, bioinformatics, or a similar field. While our lab conducts both wet and dry lab experiments, the current roles will focus on computational research. Our work explores multiple domains of biology including alternative splicing, transposable elements, and innate immunity sensing. Our research projects include analyses of multiple types of genomic data including bulk and single cell transcriptomics, spatial transcriptomics, epigenomics, and DNA sequencing.
The base salary range for this position will be $5,705-$6,000 per month, commensurate with experience and qualifications, or as mandated by a U.S. Department of Labor prevailing wage determination.
Postdoctoral scholar are represented by UAW 4121 and are subject to the collective bargaining agreement, unless agreed exclusion criteria apply. For more information, please visit the University of Washington Labor Relations website.
Qualifications
The ideal candidates will have PhDs (or foreign equivalent) in computational biology, bioinformatics, genomics, or other similar fields such as biostatistics. Applicants must have a proven publication record and a computational background is required.
Postdocs will lead projects in rheumatologic autoimmune disease and contribute to other projects on a collaborative basis.
Application Instructions
Please email Dr. Rayan Najjar (najjar@uw.edu) (1) a 1-page cover letter describing your computational experience, career objectives and research interests, (2) a CV with a list of publications (max. 3 pages), and (3) a list of three references. Please also apply at this link: https://apply.interfolio.com/144815
Equal Employment Opportunity Statement
University of Washington is an affirmative action and equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, creed, religion, national origin, sex, sexual orientation, marital status, pregnancy, genetic information, gender identity or expression, age, disability, or protected veteran status.
Benefits Information
A summary of benefits associated with this title/rank can be found at https://hr.uw.edu/benefits/benefits-orientation/benefit-summary-pdfs/. Appointees solely employed and paid directly by a non-UW entity are not UW employees and are not eligible for UW or Washington State employee benefits.
Commitment to Diversity
The University of Washington is committed to building diversity among its faculty, librarian, staff, and student communities, and articulates that commitment in the UW Diversity Blueprint (http://www.washington.edu/diversity/diversity-blueprint). Additionally, the University’s Faculty Code recognizes faculty efforts in research, teaching and/or service that address diversity and equal opportunity as important contributions to a faculty member’s academic profile and responsibilities (https://www.washington.edu/admin/rules/policies/FCG/FCCH24.html#2432).
Privacy Notice
Review the University of Washington Privacy Notice for Demographic Data of Job Applicants and University Personnel to learn how your demographic data are protected, when the data may be used, and your rights.
Disability Services
To request disability accommodation in the application process, contact the Disability Services Office at 206-543-6450 or dso@uw.edu.
Job Features
| Job Category | Health and Care, Postdoctoral |
We seek two postdoctoral fellows to join the Mustelin/Najjar lab in the Rheumatology division, University of Washington, Seattle, USA, to lead and collaborate on genomics research projects in systemic...View more
We currently have multiple postdoctoral fellowship positions within the multidisciplinary research team headed by Dr. Ajay Goel, professor and founding chair of the Department of Molecular Diagnostics and Experimental Therapeutics and associate director of basic sciences at City of Hope Comprehensive Cancer. Our multidisciplinary research group comprises basic researchers, gastroenterologists, surgeons, oncologists, and bioinformaticians, undertaking several collaborative projects involving large international consortia. Our research is focused on translational research on the genomic and epigenomic characterization of various gastrointestinal cancers (GI), including colorectal, pancreatic, gastric, esophageal, and hepatocellular cancers. Our group performs cutting-edge research in GI oncology, is very productive, and publishes in high-impact journals such as Gastroenterology, Cancer Cell, PNAS, JAMA Oncology, JNCI, Clinical Cancer Research, Nature Communications, Nature Reviews Gastroenterology and Hepatology, Annals of Surgery, etc.
Some of the key research topics in our laboratory include:
- Development of cell-free DNA (mutation and methylation), RNA, and exosomal-based liquid assays for early cancer detection, prognosis, and predictive responses to chemotherapies and targeted drugs.
- Study the genetic and epigenetic basis of GI cancers (e.g., aberrant DNA methylation, histone modifications, and non-coding RNAs).
- The genetic basis of early-onset colorectal cancer (EO-CRC) and familial/hereditary colorectal cancer.
- The role of extracellular vesicles/exosomes in cancer pathogenesis and their role as disease biomarkers.
- The role of the tumor microenvironment, stem cells, immune regulation, and identification of novel targeted therapies.
- Cancer preventive and adjunctive role of natural and integrative therapy approaches.
Key Responsibilities include:
- Devise, plan, document, and advance basic science and translational projects in genetics, epigenetics, and precision oncology of gastrointestinal cancers.
- Generate data for grant applications and prepare manuscripts for publication.
- Work closely with other team members and external collaborators, including presenting progress internally or externally.
- Ability to work in a fast-paced team environment and handle multiple projects simultaneously.
- Train and supervise technical staff.
Qualifications: Basic education, experience, and skills required for consideration:
- Ph.D., MD, or MD/Ph.D., with a strong background and profound knowledge in oncology, cancer biology, immunology, or immunotherapy.
- Ability to work in a fast-paced research environment and manage multiple projects and collaborations.
- Previous experience working with human specimens and developing novel, innovative cancer biomarkers.
- Evidence of scientific rigor and excellence as documented by high-impact peer-reviewed publications.
- Strong team player with excellent communication skills and fluency in spoken and written English.
- The individual must have effective skills in oral and written communication, teamwork, and problem-solving and be adaptable to changes in technological and scientific directions
- Commitment to the program for at least 2-3 years.
Additional Information:
- You will have the unique possibility to drive research towards a novel cancer therapy at the interface of science and translation to the clinic and publish high-impact journals.
- Please send your current CV/resume to ajgoel@coh.org, along with a cover letter highlighting your research accomplishments, a brief statement explaining how your past research ties in with the goals of our laboratory, and future career plans.
Your application should include the following in a single PDF:
- Curriculum Vitae and coordinates of three scientific mentors or references
- A cover letter highlighting your research interests, a brief statement explaining how your past research ties in with the goals of our laboratory, and future career plans.
The City of Hope is committed to creating a diverse environment and is proud to be an equal-opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex, sexual orientation, gender identity, age, status as a protected veteran, or status as a qualified individual with a disability.
Job Features
| Job Category | Postdoctoral, Sciences Biologiques |
We currently have multiple postdoctoral fellowship positions within the multidisciplinary research team headed by Dr. Ajay Goel, professor and founding chair of the Department of Molecular Diagnostics...View more
Emory University is a leading research university that fosters excellence and attracts world-class talent to innovate today and prepare leaders for the future. We welcome candidates who can contribute to the diversity and excellence of our academic community.
JOB DESCRIPTION: Helps design and conduct research within a specified field while receiving advanced training from a designated Principal Investigator to enhance professional skills and research independence needed for pursuit of a career. The specific area of research in which the trainee is mentored is determined by the department and laboratory of the Postdoc. Designs and evaluates experiments. Develops new ideas that promote current research. Prepares and publishes scientific manuscripts under the direction of the Principal Investigator. May be responsible for operation of specific equipment. May teach techniques to others, train, and supervise research staff. Positions are temporary appointments as a research trainee. The initial appointment is for one year, renewal expected if progress is satisfactory and funds are available. Appointments cannot exceed five years.
A funded postdoctoral position is available to support a collaborative project between the Seldin and Lerit labs within the Department of Cell Biology at Emory. The selected individual will work at the interface of cancer cell biology and developmental genetics using multidisciplinary approaches.
Required qualifications include an MD, PhD, MD/PhD, or equivalent degree in a biology-related discipline and a proven track record of scholarship, as evidenced through published work. Microscopy and molecular biology experience strongly preferred. Preference will be given to individuals with experience in one or more of the following: Drosophila genetics, cell culture, and/or mouse work, and cancer research.
The postdoctoral fellow will be co-mentored by Drs. Lerit and Seldin, with additional professional development opportunities provided by the Office of Postdoctoral Education at Emory
MINIMUM QUALIFICATIONS: A doctoral degree or equivalent (Ph.D., M.D., ScD., D.V.M., DDS etc) in an appropriate field. Excellent scientific writing ability and strong oral communication skills. The ability to work effectively and collegially with colleagues. Additional qualifications as specified by the Principal Investigator.
Emory University is dedicated to providing equal opportunities and equal access to all individuals regardless of race, color, religion, ethnic or national origin, gender, genetic information, age, disability, sexual orientation, gender identity, gender expression, and veteran's status. Emory University does not discriminate in admissions, educational programs, or employment on the basis of any factor stated above or prohibited under applicable law. Students, faculty, and staff are assured of participation in University programs and in the use of facilities without such discrimination. Emory University complies with Executive Order 11246, as amended, Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veteran's Readjustment Assistance Act, and applicable executive orders, federal and state regulations regarding nondiscrimination, equal opportunity and affirmative action. Emory University is committed to achieving a diverse workforce through application of its affirmative action, equal opportunity and nondiscrimination policy in all aspects of employment including recruitment, hiring, promotions, transfers, discipline, terminations, wage and salary administration, benefits, and training. Inquiries regarding this policy should be directed to the Emory University Department of Equity and Inclusion, 201 Dowman Drive, Administration Building, Atlanta, GA 30322. Emory University is committed to providing reasonable accommodations to qualified individuals with disabilities upon request. To request this document in an alternate format or to request a reasonable accommodation, please contact the Department of Accessibility Services at 404-727-9877 (V) | 404-712-2049 (TDD). Please note that one week advance notice is preferred.
Not ready to apply? Connect with us for general consideration!Job Features
| Job Category | Teaching and scientific research |
Emory University is a leading research university that fosters excellence and attracts world-class talent to innovate today and prepare leaders for the future. We welcome candidates who can contribut...View more
Our mission is to accelerate major scientific discoveries and engineering breakthroughs for humanity by designing and providing world-leading computing facilities in partnership with the computational science community. We help researchers tackle some of the world’s largest and most complex challenges with our unique combination of supercomputing resources and computational science expertise.
Our applied mathematics group is seeking a Postdoctoral Appointee to conduct research and development on differentiable and portable linear solvers tailored for advanced numerical simulations. This role will require the postdoc to work within a multi-disciplinary setting, facilitating interactions with a diverse range of experts across a broad spectrum of scientific computing, including HPC, automatic differentiation, and optimization. You will be expected to present and publish their findings at leading scientific symposia and in prestigious journals, contributing to the advancement of scalable and efficient computational methods.
Position Requirements
Required skills and qualifications:
- A recent or soon-to-completed Ph.D. (within the last 0-5 yes) in computational science with a focus on linear solvers.
- Software development skill in programming languages such as C,C++, and Julia. Experience in GPU programming.
- Effective written and oral communication skills.
- Ability to model Argonne's core values of impact, safety, respect, integrity and teamwork.
Desired skills and qualifications:
- Experience with automatic differentiation and generation of derivatives.
- Experience with machine learning methods.
Job Family
Postdoctoral Family
Job Profile
Postdoctoral Appointee
Worker Type
Long-Term (Fixed Term)
Time Type
Full time
Argonne employees, and certain guest researchers and contractors, are subject to particular restrictions related to participation in Foreign Government Sponsored or Affiliated Activities, as defined and detailed in United States Department of Energy Order 486.1A. You will be asked to disclose any such participation in the application phase for review by Argonne's Legal Department.
All Argonne offers of employment are contingent upon a background check that includes an assessment of criminal conviction history conducted on an individualized and case-by-case basis. Please be advised that Argonne positions require upon hire (or may require in the future) for the individual be to obtain a government access authorization that involves additional background check requirements. Failure to obtain or maintain such government access authorization could result in the withdrawal of a job offer or future termination of employment.
Job Features
| Job Category | Teaching and scientific research |
Our mission is to accelerate major scientific discoveries and engineering breakthroughs for humanity by designing and providing world-leading computing facilities in partnership with the computational...View more
A postdoctoral position in Ocean, Atmosphere, and Climate Dynamics is available at Yale University to join Prof. Alexey Fedorov’s group in the Department of Earth and Planetary Sciences (http://people.earth.yale.edu/profile/alexey-fedorov/about ). General fields of research include ocean and atmosphere circulation, ocean-atmosphere interactions, the ocean’s role in climate, climate variability and change. Particular focus will be on (1) ENSO and tropical climate, (2) climate links between different ocean basins, (3) stability, variability, and climate impacts of the Atlantic meridional overturning circulation (AMOC). The work will involve climate modeling, analyses of observational and GCM data, and analytical approaches. A PhD in physical oceanography, atmospheric sciences or related disciplines is required. Previous experience with climate GCMs is a big plus. Funding is currently available up to three years. Successful candidates can begin their program at Yale in the Fall of 2024; later or earlier starting dates are also possible. Review of applications will start on May 1, 2024, and will continue until the position is filled. Applicants should email their CV, a brief statement of research interests, a representative publication, and the contacts of three referees to Prof. Fedorov (alexey.fedorov@yale.edu ; subject: postdoctoral search). Shortlisted candidates will be contacted.
Yale University is an Affirmative Action/Equal Opportunity employer. Yale values diversity among its students, staff, and faculty and strongly welcomes applications from women, persons with disabilities, protected veterans, and underrepresented minorities.
Job Features
| Job Category | Postdoctoral |
A postdoctoral position in Ocean, Atmosphere, and Climate Dynamics is available at Yale University to join Prof. Alexey Fedorov’s group in the Department of Earth and Planetary Sciences (http://peop...View more
- Ph.D. in bioinformatics, data science, computational sciences, statistics or a related field.
- 3+ years of Python or R programming experience.
- Experience in bash/shell scripting and Linux environment (Ubuntu), applied statistics, high-dimensional omics data analytics for at least one type of omics.
- Excellent writing skills and independent and critical thinking ability.
- Completion of a doctoral degree in the appropriate discipline is required.
- The doctoral degree must have been completed within the five years immediately preceding the first date of appointment as a postdoctoral fellow at the University.
- The individual cannot have held previous positions in the professional ranks.
- A strong scientific publication record
- Strong quantitative/computational biology background
- Advanced computing skills, e.g., HPC, cloud
- Familiarity with data mining/data science and working with publicly available databases
- Experience in teaching academic courses and/or workshops
- Experience with grant proposals, e.g., NIH, NSF, DOE
- Collaborative and detailed-oriented
- Health insurance options including dental and vision - Health Insurance
- Generous annual and sick leave, life insurance – Faculty Benefits
- E. L. Wiegand Fitness Center offers annual or semester memberships and spouse/domestic partner membership options. E.L. Wiegand Fitness Center
- Reno is proud to be a University town! Many local businesses offer discounts to WolfCard holders
- Mountain EAP supports employees (and eligible dependents) through life's difficult moments. Mountain EAP is located in Reno and specializes in counseling and advising services for personal or interpersonal issues.
- Several Diversity Committees and Affinity Groups focusing on campus-wide diversity initiatives to ensure we are working to create a diverse and welcoming campus climate. Diversity Groups
- Faculty Senate is the principal representing body for faculty. Its membership includes representatives from each academic and administrative major unit of the University. Faculty Senate
- No state income tax!
Yes
Full-Time Equivalent100.0%
Required Attachment(s) Please note, once you submit your application the only attachment/s viewable to you will be the attachment/s to the resume/CV section of the application. Any additional required attachment/s to the cover letter, references, additional documents sections of the application, will not be viewable to you after you submit your application. All uploaded attachment/s will be on the application for the committee to review. To request updates to attachments, prior to the committee review of applications, please contact the candidate helpdesk at jobs@unr.edu Attach the following attachments to your application 1) Resume/CV 2) Cover Letter addressing personal research and career interests 3) Contact Information for Three Professional References 4) Please write a brief statement (one page maximum) about how you would contribute toward our mission of creating a culturally inclusive environment in the role for which you are applying. This posting is open until filled Qualified individuals are encouraged to apply immediately. This search will close without notice when a sufficient number of applications are received or a hiring decision has been made.Job Features
| Job Category | Postdoctoral, Sciences Biologiques |
The University of Nevada, Reno (UNR) appreciates your interest in employment at our growing institution. We want your application process to go smoothly and quickly. Final applications must be submitt...View more
- You will develop a new facility for spatially resolved electrochemical measurements, making use of a scanning probe microscope that will be upgraded with the capability for simultaneous scanning ion conductance microscopy (SICM) and scanning electrochemical microscopy (SECM).
- You will integrate a workflow of methods to determine electrocatalyst's structure-function correlations, including: i) spatially resolved methods for measuring activity using the new dual electrochemical scanning microscope; ii) correlation with existing multimodal operando vibrational microscopy and X-ray spectroscopy and iii) Machine Learning aided multimodal data analysis and reaction mechanism determination.
- You will contribute to the synthesis of thin-film and nanoparticle electrocatalyst libraries in collaboration with other members at the CFN.
- You will collaborate with scientific staff with diverse backgrounds including surface science, condensed matter physics, synchrotron X-ray science, material synthesis, data analytics, electron microscopy, physical modeling, and materials theory.
- You will disseminate research findings via paper publications and external presentations.
- You have a Ph.D. in Materials Science, Physics, Chemistry, or a related engineering discipline, conferred within the last five years or will have completed all Ph.D. requirements by the commencement of employment.
- You have demonstrated experimental expertise in scanning probe microscopy.
- You have demonstrated experience in characterization (in-situ and/or ex-situ) and data analysis for materials and/or surface science.
- You communicate effectively, verbally and in writing, evidenced by peer-reviewed publications and conference presentations/proceedings.
- You are committed to creative and independent research, teamwork, and fostering an environment of safe scientific work practices.
- You are committed to cultivating an inclusive and respectful workplace environment.
- You have experience in electrochemistry.
- You have experience in materials characterization and analysis based on surface science techniques (e.g., X-ray photoelectron spectroscopy (XPS), IR/Raman microscopy)
- You have a working knowledge of thin-film synthesis.
- You have the ability to work effectively in an interdisciplinary team to tackle challenging scientific problems.
- This is a 2 year Postdoc Assignment.
- BNL policy requires that after obtaining a PhD, eligible candidates for research associate appointments may not exceed a combined total of 5 years of relevant work experience as a postdoc and/or in an R&D position, excluding time associated with family planning, military service, illness or other life-changing events.
Job Features
| Job Category | Physical, Postdoctoral |
Details Posted: 25-Apr-24 Location: Upton, NY, Type: Full-time Salary: Open Categories: Academic/Faculty Internal Number: JR100947 Brookhaven National Laboratory is committed to employee success ...View more
- Expertise in Digital Dairy Management: Demonstrated experience and understanding of digital technologies applied to dairy management, including data-driven decision-making, precision livestock farming, and herd health monitoring.
- Interdisciplinary collaboration: Experience working in interdisciplinary research environments, collaborating with agricultural scientists, veterinarians, software engineers, and industry stakeholders to translate research findings into practical solutions for the dairy industry.
- Communication and publication Record: Excellent written and verbal communication skills, including the ability to present research findings effectively at conferences, workshops, and scientific meetings. A strong record of publications in peer-reviewed journals and conference proceedings is highly desirable.
- Experience in supervision of undergraduate and graduate students.
- Passion for innovation: Enthusiasm for exploring new technologies, methodologies, and best practices in digital agriculture, with a keen interest in driving innovation and sustainability in the dairy sector through advanced data analytics and technology integration.
- Prior relevant work or industry experience.
- Education level to the extent education is relevant to the position.
- Academic Discipline (faculty pay ranges reflects 9-month annual salary)
- Unique applicable skills.
Job Features
| Job Category | Agriculture, food and veterinary, Postdoctoral |
Postdoctoral Associate in Digital Dairy Management Postdoctoral Associate Academic Job Description Department of Animal Science Bovi-Analytics Lab/Hostens Lab Postdoctoral Associate in Digital Dairy M...View more
A Postdoctoral position is available in the lab of Dr. Jun Yang in the Department of Surgery at St Jude Children’s Research Hospital (https://www.stjude.org/directory/y/jun-yang2.html).
The Yang lab focuses on understanding how epigenetic regulators co-opt with oncogenic transcription factors to drive tumorigenesis, cancer progression and metastasis, and therapeutic resistance. His lab also actively involves drug discovery to target the epigenetic modifiers. We apply cutting-edge technologies, such as single-cell multi-omics, spatial transcriptomics, CUT&Tag, genome-wide CRISPR in vivo screening, bioinformatics, and chemical biology approaches in multiple cancer model systems including genetic mice, PDX, and organoids.
We are seeking a Postdoctoral Associate whose research will study the functions of histone demethylases in solid tumors. Candidates with training background in molecular biology, cell biology, cancer biology, and cancer immunology are welcome to apply.
Minimum Qualifications
- Ph.D. in molecular biology, cell biology, cancer biology, and cancer immunology or a related field.
- No experience required.
Diversity, Equity and Inclusion
St. Jude Children’s Research Hospital has a diverse, global patient population and workforce, built on the principles of diversity, equity and inclusion. Our founder Danny Thomas envisioned a hospital that would treat children of the world—regardless of race, religion or a family’s ability to pay. Learn more about our history and commitment .
Today, we continue the mission to advance cures and means of prevention for pediatric catastrophic diseases through research and treatment. As we accelerate this progress globally, we believe our legacy of diversity, equity and inclusion is foundational to success. With the commitment of leaders at all levels of the organization, we strive to ensure the St. Jude culture, leadership approaches and talent processes are equitable and culturally responsive. View our Diversity, Equity and Inclusion Report to learn about the hospital’s roots in diversity, equity and inclusion, where we are today and our aspirations for an even better future.
St. Jude is an Equal Opportunity Employer
No Search Firms
St. Jude Children's Research Hospital does not accept unsolicited assistance from search firms for employment opportunities. Please do not call or email. All resumes submitted by search firms to any employee or other representative at St. Jude via email, the internet or in any form and/or method without a valid written search agreement in place and approved by HR will result in no fee being paid in the event the candidate is hired by St. Jude.
Job Features
| Job Category | Health and Care, Postdoctoral |
A Postdoctoral position is available in the lab of Dr. Jun Yang in the Department of Surgery at St Jude Children’s Research Hospital (https://www.stjude.org/directory/y/jun-yang2.html). The Yang ...View more
- Organisation/Entreprise
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IMT Mines Bières
- Département
-
Département des ressources humaines
- Domaine de recherche
-
L'éthique des sciences de la santé
- Profil de chercheur
-
Chercheur principal (R4)
- Pays
-
France
- Date limite d'inscription
- Type de contrat
-
Permanent
- Statut du travail
-
À temps plein
- Le poste est-il financé par le programme-cadre de recherche de l'UE ?
-
Non financé par un programme de l'UE
- L'emploi est-il lié au poste du personnel au sein d'une infrastructure de recherche ?
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Non
Description de l'offre
- Assurer des enseignements (cours, travaux dirigés, travaux pratiques) dans la formation initiale des ingénieurs (sous statut d'étudiant ou d'apprenti) ainsi que dans les formations spécialisées de master. Il/Elle appuiera les équipes pédagogiques dans le domaine des matériaux et des sciences numériques et mécaniques, entre autres au sein du département pédagogique ECOMAP.
- Encadrer des exercices pédagogiques pour les étudiants (missions R&D, projets, PFE, etc.) notamment dans le cadre de la pédagogie-action développée par l'école (missions de terrain).
- Participer aux panels de recrutement et aux actions de promotion de la formation.
- Réaliser éventuellement un enseignement en anglais selon des méthodes pédagogiques actives ou sous forme de MOOC.
Exigences
- Domaine de recherche
- L'éthique des sciences de la santé
- niveau d'éducation
- Doctorat ou équivalent
- Expérience significative dans l'enseignement et notamment dans les nouvelles formes d'enseignement dans les domaines concernés.
- Expérience de recherche et capacité à renforcer la thématique de recherche (essais expérimentaux sur matériaux mous vivants, modélisation multi-échelles, matériaux vivants, incertitudes, modélisation de sensibilité).
- Capacité d'intégration dans le projet de l'équipe DMS, du C2MA et de l'école ; pertinence du projet d’intégration.
- Production scientifique : qualité et nombre de publications dans des revues et conférences de premier ordre, production liée à l'encadrement doctoral.
- Recherche partenariale : partenariats industriels directs, recherche collaborative, accompagnement de start-up.
- Partenariats et expérience internationale ;
- Anglais courant.
- Niveau
- Excellent
Informations Complémentaires
- Site Web pour plus de détails sur le travail
Job Features
| Job Category | Teaching and scientific research |
Organisation/Entreprise IMT Mines Bières Département Département des ressources humaines Domaine de recherche L’éthique des sciences de la santé Profil de chercheur Chercheur principal (R4)...View more
- Organisation/Entreprise
-
IMT Mines Bières
- Département
-
Département des ressources humaines
- Domaine de recherche
-
Autre
- Profil de chercheur
-
Chercheur principal (R4)
- Pays
-
France
- Date limite d'inscription
- Type de contrat
-
Permanent
- Statut du travail
-
À temps plein
- Le poste est-il financé par le programme-cadre de recherche de l'UE ?
-
Non financé par un programme de l'UE
- L'emploi est-il lié au poste du personnel au sein d'une infrastructure de recherche ?
-
Non
Description de l'offre
- Assurer des enseignements (cours, travaux dirigés, travaux pratiques) dans la formation initiale des ingénieurs (sous statut d'étudiant ou d'apprenti) ainsi que dans les formations spécialisées de master. Il/Elle épaulera les équipes pédagogiques dans le domaine de la science des matériaux et de l'économie circulaire, entre autres au sein du département pédagogique ECOMAP et du master spécialisé PRINEC co-accrédité avec IMT Mines Albi.
- Encadrer des exercices pédagogiques pour les étudiants (missions R&D, projets, PFE, etc.) notamment dans le cadre de la pédagogie-action développée par l'école (missions de terrain).
- Participer aux panels de recrutement et aux actions de promotion de la formation.
- Réaliser éventuellement des enseignements en anglais selon des méthodes pédagogiques actives ou sous forme de MOOC
- Améliorer le comportement au feu des polymères ou des composites grâce à des solutions innovantes utilisant des ressources renouvelables, des sous-produits ou des matières premières secondaires.
- L'étude des phénomènes physico-chimiques conduisant à l'altération des performances des matériaux polymères dans les conditions d'utilisation et le développement de solutions pour augmenter la durabilité de ces matériaux.
- L'étude de la valorisation de matériaux recyclés ou de déchets en de nouveaux matériaux aux propriétés fonctionnelles contrôlées.
Exigences
- Domaine de recherche
- Autre
- niveau d'éducation
- Doctorat ou équivalent
- Expérience significative dans l'enseignement et particulièrement dans les nouvelles formes d'enseignement dans les domaines concernés ;
- Expérience de recherche et capacité à renforcer le sujet de recherche (comportement au feu et cycle de vie des matériaux polymères et composites) ;
- Capacité d'intégration dans le projet de l'équipe PCH, du C2MA et de l'école ; pertinence du projet d'insertion ;
- Production scientifique : qualité et nombre de publications dans des revues et conférences de premier ordre, production liée à l'encadrement doctoral ;
- Recherche partenariale : partenariats industriels directs, recherche collaborative, soutien aux start-up ;
- Partenariats et expérience internationale ;
- Anglais courant.
- Niveau
- Excellent
- Domaine de recherche
- Autre
Informations Complémentaires
- Site Web pour plus de détails sur le travail
Job Features
| Job Category | Teaching and scientific research |
Organisation/Entreprise IMT Mines Bières Département Département des ressources humaines Domaine de recherche Autre Profil de chercheur Chercheur principal (R4) Pays France Date limite d’insc...View more
- Organisation/Entreprise
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IMT Mines Bières
- Département
-
Département des ressources humaines
- Domaine de recherche
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Sciences de l'environnement
- Profil de chercheur
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Chercheur principal (R4)
- Pays
-
France
- Date limite d'inscription
- Type de contrat
-
Permanent
- Statut du travail
-
À temps plein
- Le poste est-il financé par le programme-cadre de recherche de l'UE ?
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Non financé par un programme de l'UE
- L'emploi est-il lié au poste du personnel au sein d'une infrastructure de recherche ?
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Non
Description de l'offre
Exigences
- Domaine de recherche
- Sciences de l'environnement
- niveau d'éducation
- Doctorat ou équivalent
- Langues
- ANGLAIS
- Niveau
- Excellent
Informations Complémentaires
- Site Web pour plus de détails sur le travail
Job Features
| Job Category | Teaching and scientific research |
Organisation/Entreprise IMT Mines Bières Département Département des ressources humaines Domaine de recherche Sciences de l’environnement Profil de chercheur Chercheur principal (R4) Pays Fra...View more
- Organisation/Entreprise
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INRAÉ
- Département
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Mathématiques et technologies numériques
- Domaine de recherche
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Ingénierie » Ingénierie de contrôleMathématiques » Mathématiques appliquéesIngénierie » Génie des procédés
- Profil de chercheur
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Chercheur de première étape (R1)
- Pays
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France
- Date limite d'inscription
- Type de contrat
-
Temporaire
- Statut du travail
-
À temps plein
- Date de début de l'offre
- Le poste est-il financé par le programme-cadre de recherche de l'UE ?
-
Non financé par un programme de l'UE
- L'emploi est-il lié au poste du personnel au sein d'une infrastructure de recherche ?
-
Non
Description de l'offre
- Contexte
Les bioprocédés agroalimentaires sont encore largement sous-optimisés. Ils doivent cependant répondre à des exigences de plus en plus strictes en termes de productivité, de robustesse et de qualité des produits. Dans le contexte actuel de changement climatique, de sobriété énergétique et de hausse des coûts de l’énergie, il est également essentiel de minimiser l’impact environnemental de ces pratiques. Afin d’atteindre les objectifs de production tout en répondant aux nombreuses contraintes du procédé, le recours au contrôle devient indispensable. La théorie du contrôle a été largement utilisée dans les bioprocédés, mais a rarement été appliquée à la fermentation alcoolique pour la production de vin. La fermentation du vin est un bioprocédé réalisé dans un fermenteur, où les levures convertissent le sucre du raisin en éthanol et CO2, et la synthèse d'autres métabolites (glycérol, acides organiques, composés aromatiques, etc.) qui constituent le profil aromatique du produit final. Ces derniers comprennent les esters – et, dans une moindre mesure, les alcools supérieurs – qui contribuent directement à l’arôme fruité des vins. Jusqu’à présent, les pratiques industrielles étaient essentiellement dictées par des considérations pratiques de gestion de cave. L'objectif est généralement d'accélérer la fermentation, c'est à dire d'accélérer la conversion des sucres résiduels, plus lente en fin de fermentation (lorsque le stress éthanolique est le plus élevé pour les levures). Pour atteindre cet objectif, deux pratiques sont couramment utilisées : 1) l'ajout d'azote en début ou pendant la fermentation, et 2) la gestion anisothermique de la fermentation, qui consiste généralement à élever la température en fin de processus. Dans des travaux récents, il a été montré que ces pratiques influencent également la teneur aromatique finale du vin, avec des impacts très différents selon chaque composé aromatique. En régulant la quantité et le moment de l'ajout d'azote et en ajustant la température en temps réel, il est possible de contrôler la synthèse des arômes pendant la fermentation alcoolique et d'atteindre un objectif d'arôme et d'énergie prédéfini.
- Objectifs du projet de doctorat
L'objectif de ce projet de thèse est de contrôler la synthèse des arômes dans le vin en développant des stratégies innovantes de contrôle en temps réel du processus de fermentation alcoolique basées sur des modèles mathématiques prédictifs . Ces stratégies devront également prendre en compte de nombreuses contraintes liées au schéma de contrôle, et à la consommation énergétique de la fermentation, qui doit rester suffisamment faible. Dans des travaux antérieurs, un modèle dynamique de fermentation alcoolique du vin a été développé, qui représente les principales cinétiques, la synthèse des principaux arômes et la consommation énergétique du processus. A partir de ce modèle, une simple boucle MPC (Model Predictive Control) a été conçue et testée sur le procédé réel, ce qui constitue une preuve de concept de la démarche. En fonction du parcours et des intérêts du doctorant, plusieurs questions de recherche sont ouvertes à explorer :
- Modélisation biologique : développement de modèles mécanistiques orientés contrôle représentant la production de multiples composés aromatiques, et calibration à partir de données expérimentales. Diverses méthodes d’identification du système pourraient être envisagées et proposées ici. De plus, des techniques de réduction de modèles peuvent être testées, notamment basées sur une décomposition des dynamiques lentes/rapides (en considérant la différence de vitesses entre les voies métaboliques de l'azote et du glucose).
- Contrôle temps réel : conception de nouvelles lois de contrôle, prenant en compte des aspects tels que la performance et la robustesse face à l'incertitude du modèle. La gamme de méthodes peut varier des lois de contrôle par rétroaction non linéaires et éventuellement adaptatives pour les systèmes avec contraintes d'entrée, aux algorithmes de contrôle basés sur l'optimalité (comme les boucles MPC). Les problèmes d’observabilité sont également intéressants pour l’estimation d’état en ligne dans des implémentations en temps réel.
Le projet impliquera une étude théorique du problème mathématique, des simulations numériques et une validation expérimentale des lois de contrôle à appliquer et tester sur le procédé réel situé à l'Unité Expérimentale Pech Rouge à Gruissan.
- Mots clés
Théorie du contrôle, fermentation du vin, synthèse des arômes, modèles biologiques, système dynamique
- Compétences requises
Nous recherchons une formation en modélisation biologique , en automatique ou en mathématiques appliquées avec un goût pour les applications. La connaissance des processus ou systèmes biologiques n'est pas requise, mais recommandée. De bonnes compétences en programmation sont requises (Python et/ou Matlab et/ou R).
- À propos du centre de recherche
Le doctorant sera basé à l' UMR MISTEA (Mathématiques Informatique et Statistiques pour l'Environnement et l'Agronomie), sur le campus Gaillarde de Montpellier SupAgro . Le stage sera encadré par Agustin Yabo et Céline Casenave, tous deux chercheurs à l'INRAE (Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement) travaillant dans le domaine de la modélisation et du contrôle des systèmes biologiques. Le projet se déroulera en collaboration avec l'UMR SPO (Sciences pour l'Œnologie), l'Unité Expérimentale INRAE Pech Rouge et potentiellement des partenaires privés.
- informations générales
Durée : 36 mois Localisation : Montpellier, France Salaire brut mensuel : 2100€ (1ère année), 2200€ (2ème année) et 2300€ (3ème année) 1 Date d'entrée : Entre septembre et décembre 2024 Avantages : tarif réduit cantine, gratuit transports publics 2 , sécurité sociale, congés payés, horaires de travail flexibles
- Contacts
Agustin G. Yabo : agustin.yabo@inrae.fr - www.agustinyabo.com.ar
Céline Casenave : celine.casenave@inrae.fr - celinecasenavefr.wordpress.com
- Les références
Beaudeau et coll. (2023). Modélisation dynamique des effets de l'ajout d'azote assimilable sur la synthèse des arômes lors de la fermentation du vin. Transactions de génie chimique , 102 , 301-306.
Casenave, C. et Montseny, E. (2017). Simplification de problèmes dynamiques par transformation temporelle : application à la commande non linéaire avec contraintes positives d'entrée. Congrès mondial de l'IFAC 2017.
Casenave et coll. (2019). Stratégie de linéarisation entrée-sortie anti-enroulement pour le contrôle d'un fermenteur continu à plusieurs étages avec contraintes d'entrée. Transactions IEEE sur la technologie des systèmes de contrôle , 28 (3), 766-775.
Godillot et coll. (2023). Analyse des cinétiques de production de composés volatils : étude de l'impact de l'ajout d'azote et de la température lors de la fermentation alcoolique. Frontières en microbiologie , 14 , 1124970.
Yabo, AG et Casenave, C. (2022). Synthèse des arômes et consommation d'énergie dans la fermentation du vin : une approche d'optimisation multi-objectif. Congrès mondial de l'IFAC 2024.
Ritonja, J. et coll. (2023). Approches pratiques du contrôle de la fermentation du lait avec les grains de kéfir. IntechOpen.
Job Features
| Job Category | Mathematics and statistics, Doctorat, Ingénierie et technologie |
Organisation/Entreprise INRAÉ Département Mathématiques et technologies numériques Domaine de recherche Ingénierie » Ingénierie de contrôle Mathématiques » Mathématiques appliquées Ingéni...View more
- Organisation/Entreprise
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CNRS
- Département
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Laboratoire des sciences du numérique à Nantes
- Domaine de recherche
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La physique
- Profil de chercheur
-
Chercheur de première étape (R1)
- Pays
-
France
- Date limite d'inscription
- Type de contrat
-
Temporaire
- Statut du travail
-
À temps plein
- Heures par semaine
-
35
- Date de début de l'offre
- Le poste est-il financé par le programme-cadre de recherche de l'UE ?
-
H2020
- L'emploi est-il lié au poste du personnel au sein d'une infrastructure de recherche ?
-
Non
Description de l'offre
Exigences
- Domaine de recherche
- La physique
- niveau d'éducation
- Doctorat ou équivalent
- Langues
- FRANÇAIS
- Niveau
- Basique
- Domaine de recherche
- La physique
- Années d'expérience en recherche
- Aucun
Informations Complémentaires
- Site Web pour plus de détails sur le travail
Job Features
| Job Category | Physical, Postdoctoral |
Organisation/Entreprise CNRS Département Laboratoire des sciences du numérique à Nantes Domaine de recherche La physique Profil de chercheur Chercheur de première étape (R1) Pays France Date limi...View more