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The salary is according to German public service salary scale level TV-L 13 starting as soon as possible, the position Single Cell is limited for 3 years with 65% and the position Epigenomic Bioinformatics is limited for 2 years with 65%.
We invite applicants for a PhD position in (1) integrative analysis of single cell transcriptomics and open chromatin data to dissect fibrosis on kidney diseases and (2) computational methods to dissect DNA methylation changes and their impact in regulatory features of cells upon aging in humans. The candidates will develop bioinformatic methods for (1) tracking temporal changes of single cells, to perform integrative analysis of scRNA-seq, scATAC-seq and/or spatial information and (2) associated DNA methtylation changes from whole genome bisulfite sequencing (WGBS) with chromatin, regulatory and transcriptional features of cells (ATAC-seq, ChIP-seq, scATAC-seq and scRNA-seq). Projects will be performed in close collaboration with the clinical and molecular scientists and implemented within the DFG funded research consortias “Integrating emerging methods to advance translational kidney research (InteraKD) and “Genome Wide Analysis of Epigenetic Changes in Aging (GERAS)”.
Profil:
• Highly motivated individuals with a university degree (M.Sc. or equivalent) in computer science or bioinformatics.
• Experience in bioinformatics methods for analysis of single cell sequencing and statistical machine learning.
• Experience in high performance computing is a plus.
• Willingness for teamwork and the ability to work independently in a competitive international environment are required.
• Good skills of English are expected.
We offer a dynamic, interdisciplinary and international environment with a focus on translational medicine and provide all advanced technologies of modern biomedicine. With 40000 students and 6000 academic staff, the RWTH is one of the largest universities in Germany.
This advertisement is adressed to all genders. The RWTH Aachen University Hospital promotes equal opportunities and diversity. Applications from women are expressly encouraged and will be given priority in accordance with the LGG. Employment below the weekly working hours specified above is generally possible. Severely disabled people will be given priority if they are equally qualified.
Please send your application with all documents including a curriculum vitae, a letter of motivation, all academic certificates and 2-3 references to ivan.costa@rwth-aachen.de.
The application period for the advertised position ends on 20.10.2021. For further information, please contact: Univ.-Prof. Dr. Prof. Ivan G. Costa, E-Mail: ivan.costa@rwth-aachen.de
