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A postdoctoral fellowship position is available in Dr. Abhishek Chakraborty’s laboratory in the Department of Cancer Biology at the Lerner Research Institute, Cleveland Clinic. The laboratory is part of Cleveland Clinic’s Genitourinary Malignancies Research Center and has close ties to both basic researchers and clinicians at the Cleveland Clinic and the broader Case Comprehensive Cancer Center in Cleveland, OH.
Dr. Chakraborty has many years of training in hypoxia biology and kidney cancer, and has published manuscripts in top-tier journals. The laboratory utilizes a wide array of technical expertise ranging from basic biochemistry and molecular biology to advanced genomics, including RNA-Seq, ChIP-Seq, and single-cell ATAC/RNA-Seq. The laboratory routinely employs unbiased genetic (e.g. CRISPR/Cas9) and pharmacological (e.g. drug library) screens to identify novel mechanisms driving dysregulated hypoxic response. The laboratory is well-funded with federal and non-federal research grants, and foundation awards. Ongoing projects in the laboratory are interrogating:
· Hypoxic cell state control in breast cancer using pharmacological and genetic screens;
· Actionable epigenetic and metabolic dependencies in kidney cancer; and
· The role of hypoxia in lineage-specification during animal development.
The ideal candidate would have a M.D., Ph.D., or an M.D./Ph.D., and be self-motivated, collegial, and hard-working. Candidates should be eager to learn and have a strong commitment to basic research, but past experience in cancer biology is not essential. Salary will be commensurate with individual experience (and corresponding NIH recommendations) and the Cleveland Clinic offers excellent heathcare benefits. Our laboratory values diversity, equity, and inclusion. Women, underrepresented minorities, and LGBTQ individuals are encouraged to apply. Visa applications, as necessary, will be supported for qualified individuals.
Cleveland Clinic is consistently ranked among the top medical centers in America by U.S. News (2020-21: No. 2 in the overall rankings and No. 5 as a Cancer Center). This post-doctoral position provides a unique opportunity to study chromatin function, tumor metabolism, molecular oncology, and drug development, in collaboration with clinical investigators who can translate these findings, in a world class clinical/research center.
Candidates with an interest in the position should email their Cover letter, CV or Biosketch, and contact information for 3 references to:
Abhishek A. Chakraborty
Dept of Cancer Biology
Lerner Research Institute
Cleveland Clinic, OH
